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. 2019 Aug 23;11(9):1236. doi: 10.3390/cancers11091236

Figure 3.

Figure 3

The classical MAPK pathway and a simplified NF-kB pathway. This pathway is of particular interest because of TGFβ’s ability to induce signalling through receptor recognition and signal amplification. The pathway is also of interest because of its endpoints, namely activation of p53 and various cytokines.