Figure 3.

OPN is important in the maintenance of fetal HSC pools. (a) A summary of incidence and content of SLAM HSC in the fetal and neonatal BM. Data represents the cell content after normalization by mouse weights. (b) Cell cycle analysis with Ki67 and Hoechst on D2 BM LSKSLAM cells. Each dot represents the average value for a litter (for fetal) or an individual mouse from different litters (for newborn). WT: closed black circle; OPN^-/-: open red circle; * p < 0.05, ** p < 0.01. Data shows mean ± SEM, n ≥ 3.