Table 3.
Multivariable Cox regression analysis estimating the influence of FGF 8, FGF 18 and FGFR 4 expression on overall survival for patients with adenocarcinoma of the esophago-gastric junction.
| All Patients | Neoadjuvantly Treated Patients | Primarily Resected Patients | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Factors | Hazard Ratio | 95% CI | p Value | Hazard Ratio | 95% CI | p Value | Hazard Ratio | 95% CI | p Value |
| FGF 8 (ref.: high) | |||||||||
| low/absent | 0.68 | (0.46–0.99) | 0.042 | 0.43 | (0.22–0.82) | 0.011 | 1.04 | (0.63–1.72) | 0.882 |
| FGF 18 (ref.: low/absent) | |||||||||
| high | 0.71 | (0.48–1.04) | 0.08 | 0.44 | (0.22–0.86) | 0.017 | 0.81 | (0.49–1.33) | 0.408 |
| FGFR 4 (ref.: high) | |||||||||
| low/absent | 1.04 | (0.72–1.50) | 0.834 | 1.02 | (0.58–1.81) | 0.945 | 1.03 | (0.63–1.67) | 0.908 |
CI = confidence interval; FGF = fibroblast growth factor; FGFR = fibroblast growth factor receptor.