Fig. 1.

Treatment algorithm for nonalcoholic fatty liver disease. This treatment algorithm shows a practical approach to be used clinically to identify patients at highest risk for nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, and fibrosis. AST, aspartate aminotransferase; ALT, alanine aminotransferase; ANA, anti-nuclear antibody, ASMA, anti-smooth muscle antibody; NAFLD, nonalcoholic fatty liver disease; NASH, nonalcoholic steatohepatitis; MRE, magnetic resonance elastography; APRI, AST to platelet ratio index; FIB-4, fibrosis-4 index for liver fibrosis