Table 1.
Correlation of the expression of the hsa_circ_0000479 and clinical features of SLE.
| Clinical characteristics | N | hsa_circ_0000479 | P-value# | |
|---|---|---|---|---|
| Anti-ds-DNA antibody | Positive | 27 | 0.0028 ± 0.0037 | 0.279 |
| Negative | 31 | 0.0030 ± 0.0032 | ||
| Anti-Rib-P antibody | Positive | 12 | 0.0031 ± 0.0033 | 0.443 |
| Negative | 46 | 0.0029 ± 0.0035 | ||
| Anti-Smith-antibody | Positive | 12 | 0.0034 ± 0.0032 | 0.249 |
| Negative | 46 | 0.0028 ± 0.0035 | ||
| Anti-SSA antibody | Positive | 33 | 0.0032 ± 0.0035 | 0.435 |
| Negative | 25 | 0.0025 ± 0.0033 | ||
| Anti-SSB antibody | Positive | 7 | 0.0031 ± 0.0037 | 0.591 |
| Negative | 51 | 0.0029 ± 0.0034 | ||
| Direct Coomb's test | Positive | 8 | 0.0046 ± 0.0049 | 0.291 |
| Negative | 33 | 0.0021 ± 0.0027 | ||
| Indirect Coomb's test | Positive | 4 | 0.0021 ± 0.0014 | 0.596 |
| Negative | 37 | 0.0027 ± 0.0034 | ||
| β2-GP1 | Positive | 11 | 0.0014 ± 0.0021 | 0.242 |
| Negative | 26 | 0.0019 ± 0.0020 | ||
| Anticardiolipin antibody IgG | Positive | 21 | 0.0042 ± 0.0043 | 0.028 |
| Negative | 31 | 0.0018 ± 0.0019 | ||
| Lupus anticoagulant | 0.75 ~ 1.25 | 23 | 0.0034 ± 0.0036 | 0.115 |
| >1.25 | 13 | 0.0019 ± 0.0026 | ||
| Leukocytes | 0 ~ 3.0 | 7 | 0.0053 ± 0.0048 | 0.043 |
| >3.0 | 53 | 0.0026 ± 0.0030 | ||
| Hemoglobin | <110 | 36 | 0.0034 ± 0.0035 | 0.015 |
| 110 ~ 150 | 24 | 0.0021 ± 0.0030 | ||
| Platelet | 100 ~ 350 | 44 | 0.0027 ± 0.0031 | 0.813 |
| <100 | 14 | 0.0030 ± 0.0037 | ||
| Albumin | <40 | 39 | 0.0034 ± 0.0035 | 0.002 |
| ≥40 | 13 | 0.0012 ± 0.0021 | ||
| ALT | >75 | 5 | 0.0045 ± 0.0041 | 0.255 |
| 0 ~ 75 | 55 | 0.0027 ± 0.0033 | ||
| AST | >35 | 13 | 0.0033 ± 0.0034 | 0.293 |
| 0 ~ 35 | 41 | 0.0030 ± 0.0033 | ||
| C3* | <0.9 | 50 | 0.0028 ± 0.0033 | 0.214 |
| 0.9 ~ 1.8 | 9 | 0.0038 ± 0.0038 | ||
| C4* | <0.1 | 24 | 0.0033 ± 0.0035 | 0.419 |
| 0.1 ~ 0.4 | 33 | 0.0025 ± 0.0031 | ||
| Urine protein | Positive | 28 | 0.0038 ± 0.0035 | 0.005 |
| Negative | 26 | 0.0021 ± 0.0033 | ||
| Urine occult blood | Positive | 16 | 0.0029 ± 0.0034 | 0.860 |
| Negative | 39 | 0.0029 ± 0.0035 | ||
| Serum creatinine | >104 | 13 | 0.0038 ± 0.0041 | 0.280 |
| 45 ~ 104 | 38 | 0.0026 ± 0.0034 | ||
| Total IgG | >16 | 18 | 0.0045 ± 0.0045 | 0.021 |
| ≤ 16 | 37 | 0.0022 ± 0.0026 | ||
| Total IgM | >2.3 | 2 | 0.0029 ± 0.0006 | 0.421 |
| ≤ 2.3 | 54 | 0.0029 ± 0.0035 | ||
| Total IgA | >4.0 | 6 | 0.0040 ± 0.0048 | 0.703 |
| ≤ 4.0 | 49 | 0.0028 ± 0.0033 | ||
| CRP | 0 ~ 8 | 46 | 0.0026 ± 0.0032 | 0.089 |
| >8 | 12 | 0.0038 ± 0.0038 | ||
| ESR | 0 ~ 20 | 30 | 0.0017 ± 0.0024 | 0.0002 |
| >20 | 28 | 0.0041 ± 0.0039 | ||
| D-Dimer | 0.00 ~ 0.50 | 14 | 0.0023 ± 0.0029 | 0.052 |
| >0.5 | 21 | 0.0041 ± 0.0040 |
*
C3/C4, complement 3/complement 4.
The bold values indicated P < 0.05.