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. 2019 Sep 6;10(9):687. doi: 10.3390/genes10090687

Table 4.

Sequence types that showed significant increases or decreases over the time period (deduplicated data).

ST % of Isolates per Study Exact Test for Change
between Years
Comment
2002
N = 283
2009
N = 100
2013
N = 131
2016
N = 160
2018
N = 54
9 5.7 *** Decrease post 2002
124 5.3 *** Decrease post 2002
311 5.3 ** Decrease post 2002
176 9.9 4.0 *** Decrease post 2002
36 5.7 1.0 *** Decrease post 2002
65 3.9 4.0 ** Decrease post 2009
439 6.0 6.9 3.1 *** Increase post 2002
1262 3.0 3.8 6.2 3.7 *** Increase post 2002
1635 7.4 1.9 *** Increase post 2009
2372 0.8 3.8 7.4 *** Increase post 2013
4149 1.3 7.4 *** Increase post 2013
3811 5.6 *** Increase post 2016
62 3.2 11.0 12.2 8.8 11.1 ** Increase post 2009
177 0.7 3.1 1.9 7.4 * Increase post 2009

*** p < 0.0001, ** p < 0.001, * p < 0.01.