Table 1.
Clinical Factors and Day 180 Outcomes by ICH Location and Thalamic vs. Non-Thalamic ICH Location
| Location | N (%) | Age, Mean (SD) |
Female, n (%) |
Admission GCS, Median (IQR) |
ICH Volume (mL), Mean (SD) |
IVH Volume (mL), Mean (SD) |
Mortality, n (%) |
mRS 4–6, n (%) |
NIHSS >4, n (%) |
SIS <60, n (%) |
BI ≤85, n (%) |
EQ-VAS <70, n (%) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Thalamus | 332 (71.1) | 58.6 (10.4) | 137 (41.3)* | 10 (6–14) | 11.5 (6.87)*** | 24.13 (18.18)*** | 84 (25.8)* | 123 (50.8)*** | 109 (50.7)*** | 114 (52.3)*** | 150 (63.3)*** | 137 (64.6)** |
| Non-thalamus | 135 (28.9) | 58.5 (13.0) | 67 (49.6) | 10 (7–14) | 5.89 (7.41) | 39.81 (23.04) | 26 (19.5) | 29 (27.1) | 21 (20.8) | 32 (30.8) | 39 (36.8) | 48 (47.5) |
| Caudate | 219 (46.9) | 59.7 (11.5) | 99 (45.2) | 9 (6–13) | 10.73 (7.82) | 36.54 (21.65) | 52 (24.2) | 81 (49.4) | 73 (48.3) | 70 (46.4) | 96 (59.6) | 89 (59.3) |
| PLIC | 188 (40.3) | 59.0 (10.4) | 74 (39.4) | 11 (7–14) | 13.77 (7.22) | 25.33 (20.29) | 52 (27.8) | 82 (60.7) | 76 (61.8) | 76 (60.3) | 99 (75.0) | 85 (70.8) |
| ALIC | 108 (23.1) | 59.2 (11.8) | 58 (53.7) | 8.5 (6–13) | 12.43 (8.28) | 30.96 (19.72) | 21 (19.4) | 39 (44.8) | 31 (40.8) | 39 (49.4) | 43 (51.2) | 42 (54.5) |
| GP/P | 127 (27.2) | 58.8 (11.8) | 62 (48.8) | 9 (6–13) | 14.86 (7.63) | 28.22 (17.84) | 35 (27.8) | 52 (56.5) | 49 (60.5) | 49 (59.8) | 62 (70.5) | 54 (66.7) |
| Lobar | 29 (6.2) | 60.24 (11.15) | 16 (55.2) | 11 (7–15) | 15.84 (8.65) | 34.58 (23.49) | 10 (34.5) | 4 (21.1) | 5 (27.8) | 4 (22.2) | 7 (36.8) | 7 (38.9) |
Comparison of thalamus vs. non-thalamus for each variable (t-test, rank sum test, or chi-square test). BI indicates Barthel Index; EQ-VAS, EuroQol Visual Analogue Scale; GP/P, globus pallidus/putamen; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; and SIS, Stroke Impact Scale.
*
P<0.05.
**
P<0.01
***
P<0.001.