Fig. 1.

Downregulated PGM5 in CRC is associated with poor prognosis. a The PGM5 expression on Box Plotsacross all tumor samples and paired normal tissues in TCGA (Match TCGA normal and GTEx data, P < 0.001). Each dots represent expression of samples; b the expression level of PGM5 mRNA using RT-PCR; c representative images of PGM5 IHC staining in CRC and normal tissues (×200, scale bar 100 μm); d PGM5 protein expression in CRC tissues and adjacent tissues; e Kaplan–Meier analysis of the relationship between overall survival and PGM5 expression in patients with CRC; f The PGM5 expression in CRC cells. PGM phosphoglucomutase, CRC colorectal cancer, TCGA The Cancer Genome Atlas, IOD integrated optical density, qRT-PCR quantitative real-time PCR, IHC immunohistochemistry; **< 0.001