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. 2019 Aug 13;3(10):1311–1321. doi: 10.1002/hep4.1417

Table 1.

Sociodemographic and Health Characteristics of the Sample Stratified by NAFLD Status

Non‐NAFLD (n = 337) NAFLD (n = 222) P value*
N Obs Estimate N (%) Estimate
Age, mean (SD) 337 13.7 (4.0) 222 13.6 (2.9) 0.687
Sex, count (%)
Male 337 132 (39.1) 222 135 (60.8) <0.001
Race/ethnicity, count (%)
Non‐Hispanic black 337 132 (38.9) 222 25 (11.3) <0.001
Non‐Hispanic white 128 (37.8) 70 (31.5) 0.16
Hispanic 66 (19.5) 121 (54.5) <0.001
Asian/other 10 (2.9) 4 (1.8) 0.75
Weight status, count (%)
Normal/underweight 332 100 (29.4) 222 4 (1.8) <0.001
Overweight 45 (13.6) 15 (6.8) 0.027
Obese 187 (57.0) 203 (91.4) <0.001
Waist circumference, mean (SD) 237 96.0 (18.98) 140 104.3 (17.91) <0.001
Hip circumference, mean (SD) 236 104.9 (16.46) 140 107.0 (16.93) 0.24
Fasting glucose (mg/dL), mean (SD) 328 87.9 (12.7) 220 88.3 (12.4) 0.69
2‐Hour glucose (mg/dL), mean (SD) 233 117.7 (29.7) 115 127.2 (33.9) 0.012
Fasting insulin (mg//dL), mean (SD) 238 27.8 (22.8) 138 37.9 (21.5) <0.001
WBISI, mean (SD) 226 2.4 (1.54) 113 1.5 (0.79) <0.001
Insulinogenic index, mean (SD) 218 4.7 (5.47) 112 5.6 (4.58) 0.15
Disposition index, mean (SD) 217 9.3 (16.64) 112 7.1 (6.10) 0.19
HOMA‐IR, mean (SD) 238 6.3 (5.38) 138 8.7 (5.33) <0.001
HBA1C (%), mean (SD) 204 5.5 (0.28) 97 5.5 (0.34) 0.07
Diabetes diagnoses, count (%)
Type 2 diabetes 328 8 (2.7) 220 4 (2.3) 0.99
Impaired glucose tolerance 233 40 (17.2) 115 26 (22.6) 0.28
Impaired fasting glucose 328 26 (10.2) 220 24 (14.0) 0.69
ALT (U/L), median (IQR) 308 19 (28) 204 24 (27) <0.001
AST (U/L), median (IQR) 307 43 (65.3) 203 32 (24.5) <0.001
Total‐C (mg/dL), mean (SD) 304 158.4 (41.2) 203 163.8 (37.9) 0.13
Triglycerides (mg/dL), mean (SD) 304 89.3 (56.7) 203 130.9 (71.6) <0.001
HDL‐C (mg/dL), mean (SD) 304 46.7 (13.8) 203 43.9 (10.9) 0.010
LDL‐C (mg/dL), mean (SD) 304 93.8 (38.0) 203 96.7 (32.3) 0.34
*

P values calculated using Student t tests or chi‐square tests. For ALT and AST, nonparametric Mann‐Whitney U test was performed due to non‐normality of the variables. Bold values indicate clinically important differences between groups.

Abbreviations: C, cholesterol, HBA1C, hemoglobin A1C; IQR, interquartile range.