Table 1.
Antiproliferative activity against human colon cancer cell line HCT116 by compounds 7-18
| Compd | Alternative name | HCT116 |
|---|---|---|
| GI50 (μM±SD) | ||
| 14 | MPT0B369 | 0.06 ± 0.00 |
| 7 | MPT0B390 | 0.03 ± 0.01 |
| 9 | MPT0B515 | 0.09 ± 0.03 |
| 8 | MPT0B517 | 0.17 ± 0.07 |
| 10 | MPT0B519 | 0.14 ± 0.05 |
| 11 | MPT0B522 | 5.1 ± 0.7 |
| 12 | MPT0B524 | 5.46 ± 0.9 |
| 13 | MPT0B534 | 2.91 ± 1.01 |
| 15 | MPT0B553 | 0.07 ± 0.03 |
| 16 | MPT0B554 | 1.58 ± 1.05 |
| 17 | MPT0B555 | 1.65 ± 0.31 |
| 18 | MPT0B556 | 5.46 ± 0.81 |
aSD: standard deviation. All experiments were independently performed at least three times.