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. 2019 Sep 24;10:846. doi: 10.3389/fgene.2019.00846

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Copyright © 2019 Battaglia, Venturin, Sojic, Jesuthasan, Orro, Spinelli, Musicco, De Bellis and Adorni

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MCODE enrichment analysis by Metascape. (A) PPI interaction network. MCODE algorithm was applied to clustered enrichment ontology terms to identify neighborhoods where proteins are densely connected. Each MCODE network is assigned a unique color. (B) PPI MCODE component. GO enrichment analysis was applied to each MCODE network to assign “meanings” to the network component. See Supplementary Table S5 for more details. Red, blue, green, and violet colors indicate modules 1, 2, 3, and 4, respectively.