Table 1.

Top ranked clusters of enrichment terms of Module 1.

GO Biological Processes and KEGG terms*	Genes
GO:0043068-positive regulation of programmed cell death	CDKN2A, ATF2, GSK3A, MAPT, PPARG, SNCA, SOD1, SOS1, TP53, SQSTM1, HDAC6, PPARGC1A
GO:0034599-cellular response to oxidative stress	EGFR, MAPT, PRKAA1, SNCA, SOD1, TP53, BECN1, HDAC6, PPARGC1A
GO:0061919-process utilizing autophagic mechanism	GSK3A, MAPT, PRKAA1, SNCA, TP53, UCHL1, BECN1, SQSTM1, HDAC6, PPARGC1A
hsa05214: Glioma	CDKN2A, EGF, EGFR, IGF1R, KRAS, SOS1, TP53
hsa04211: Longevity regulating pathway	ATF2, IGF1R, KRAS, PPARG, PRKAA1, TP53, PPARGC1A

*Selected enrichment categories of Module 1. For more details, see Supplementary Table S4 .