Table 3.

List of miRNAs and their target genes belonging to PPI modules.

PPI module	miRNA ID	Target genes (miRTarBase)
Module 1	hsa-miR-16-5p	EGFR, CDKN2A, KRAS, SQSTM1, HSPA9, TP53, IGF1R, ALDH2, PRKAA1
	hsa-miR-30a-5p	STUB1, EGFR, BECN1, TP53, IGF1R, PRKAA1
	hsa-miR-27a-3p	EGFR, KRAS, TP53, PPARG, SOS1
	hsa-miR-206	KRAS, SOD1, IGF1R
	hsa-miR-125b-5p	EGFR, CDKN2A, TP53, IGF1R
	hsa-miR-125b-1-3p	TP53, IGF1R
	hsa-miR-7-5p	EGFR, SQSTM1, IGF1R, SNCA
	hsa-miR-146a-5p	EGFR, SQSTM1, SOS1
	hsa-miR-21-5p	STUB1, EGFR, ATF2, IGF1R
	hsa-miR-548e-5p	BECN1, SQSTM1, PRKAA1
	hsa-miR-877-5p	KRAS, SQSTM1, UCHL1
	hsa-miR-34a-5p	CDKN2A, BECN1, TP53, IGF1R
	hsa-miR-150-3p	TP53, IGF1R
Module 2	hsa-miR-9-5p	NOTCH1, ESR1, GSK3B
	hsa-miR-744-5p	PIN1, GSK3B, PRKACA
	hsa-miR-1910-5p	ESR1, GSK3B
	hsa-miR-296-5p	NOTCH1, PIN1
	hsa-miR-874-3p	ESR1, PIN1
	hsa-miR-6073	ESR1, APP
	hsa-miR-935	NOTCH1, PSEN1
	hsa-miR-4709-3p	ESR1, APP
	hsa-miR-22-3p	ESR1, PRKACA
Module 3	hsa-miR-34a-5p	BRCA1, CTNNB1, WNT1
	hsa-miR-139-5p	HSP90AA1, WNT1
	hsa-miR-152-3p	HSP90AA1, WNT1
	hsa-miR-548l	HSP90AA1, CTNNB1
	hsa-miR-148a-3p	HSP90AA1, WNT1
	hsa-miR-1226-3p	HSP90AA1, CTNNB1
	hsa-miR-1826	CTNNB1
	hsa-miR-101-3p	HSP90AA1, CTNNB1
	hsa-miR-148b-3p	HSP90AA1, WNT1
	hsa-miR-375	HSP90AA1, CTNNB1

Bold, miRNA associated with both Alzheimer’s disease and cancer based on the Human microRNA Disease Database (HMDD v3.0).