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. 2019 Oct;9(10):a033514. doi: 10.1101/cshperspect.a033514

Figure 4.

Figure 4.

Compressional radial waves and longitudinal traveling waves in Col11a2 mutant tectorial membranes (TMs). (A) Wave chamber setup depicting stimulation of compressional waves along the radial direction of the TM. (B) Phase accumulation of motion along the TM’s radial fibrillar structure. Deletion of Col11a2 increases the amount of phase accumulation along the radial direction and thus could impact outer hair cell (OHC)–inner hair cell (IHC) coupling mechanisms. (C) Wave chamber setup depicting stimulation of longitudinal traveling waves along the TM. (D) Deletion of Col11a2 increases the amount of phase accumulation along the longitudinal direction and thus reduces TM traveling wave speed. Reduced TM wave speed may cause mismatches with basilar membrane (BM) wave speed and thus affect the sensitivity of hearing in Col11a2−/− mice.