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. 2019 Oct 2;367:l5205. doi: 10.1136/bmj.l5205

Table 1.

Summary of detected changes in prescription behaviour for two prescribing measures, across all general practices (move from branded to generic versions of desogestrel in 2012 and change from trimethoprim to nitrofurantoin as the firstline antibiotic for treating uncomplicated urinary tract infection (UTI) at various time points after 2014)

Prescribing measure Timing (months from intervention) Steepness (% change per month) Magnitude (% change)
Desogestrel
Median 8 8.9 65.9
Interquartile range 2-14 2.0-28.3 43.7-85.0
Mean 6.7 18.7 61.7
Standard deviation 12.5 24.2 27.6
UTI antibiotics*
Median 18 2.1 37.7
Interquartile range 5-29 1.0-7.5 28.4-47.0
Mean 15.8 6.9 37.9
Standard deviation 14.3 12.4 14.7
*

For the UTI measure, timing is in relation to the first intervention (October 2014, the change in Public Health England guidance).