Figure 1. Photomicrographs of the lung nodule. A – Poorly differentiated chordoma. The tumor is composed of sheets of epithelioid cells with eosinophilic cytoplasm (H&E, 100X); B – Poorly-differentiated chordoma. Notice the well-formed granuloma and the cells with clear cytoplasm in the lower right corner (H&E, 100X); C – Poorly-differentiated chordoma. Focal areas show tumor cells with clear to vacuolated cytoplasm admixed with epithelioid cells (H&E 200X); D – Pankeratin immunohistochemical stain highlighting the lesional cells (Pankeratin immunohistochemical stain, 100X).