Table 1.

Significantly changed proteins revealed by comparative proteomic analysis of liver mitochondria from mice at different temperatures.

Groups	Pattern	Number of proteins	UniProtKB Accession Number	Protein description	Gene name	Ratio	P value
T 6 vs. T 23	Up‐regulated	18	Q14DH7	Acyl‐CoA synthetase short‐chain family member 3	Acss3	1.46	0.06
			Q91X75	Cyp2a4 protein	Cyp2a5	1.38	0.10
			O70400	PDZ and LIM domain protein 1	Pdlim1	1.36	0.07
			Q8K0L3	Acyl‐coenzyme A synthetase ACSM2	Acsm2	1.35	0.04
			Q505D7	Optic atrophy 3 protein homolog	Opa3	1.33	0.02
			P29758	Ornithine aminotransferase	Oat	1.32	0.01
			Q9WVM8	Kynurenine/alpha‐aminoadipate aminotransferase	Aadat	1.29	0.03
			Q9QZA0	Carbonic anhydrase 5B	Ca5b	1.25	0.07
			Q504M2	MCG53395	Pdp2	1.25	0.09
			D3YYS6	Monoglyceride lipase	Mgll	1.25	0.07
	Down‐regulated	59	Q8VCF0	Mitochondrial antiviral‐signalling protein	Mavs	0.34	0.09
			Q8BSE0	Regulator of microtubule dynamics protein 2	Rmdn2	0.39	0.06
			Q9CZW5	Mitochondrial import receptor subunit TOM70	Tomm70	0.52	0.06
			Q8BH80	Vesicle‐associated membrane protein, associated protein B and C	Vapb	0.52	0.10
			Q9WV55	Vesicle‐associated membrane protein‐associated protein A	Vapa	0.52	0.07
			Q3UJU9	Regulator of microtubule dynamics protein 3	Rmdn3	0.52	0.06
			F6U775	Dynamin‐like 120 kDa protein	Opa1	0.56	0.06
			P13516	Acyl‐CoA desaturase 1	Scd1	0.57	0.03
			O70303	Cell death activator CIDE‐B	Cideb	0.62	0.03
			Q8VDJ3	Vigilin	Hdlbp	0.63	0.02
T 6 vs. T 30	Up‐regulated	175	P70670	Nascent polypeptide‐associated complex subunit alpha	Naca	2.44	0.04
			Q9CXV1	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit	Sdhd	2.23	0.02
			D3YVW2	Golgi integral membrane protein 4	Golim4	2.16	0.01
			P22599	Alpha‐1‐antitrypsin 1–2	Serpina1b	2.13	0.05
			Q8BWY3	Eukaryotic peptide chain release factor subunit 1	Etf1	1.97	0.10
			Q91X75	Cyp2a4 protein	Cyp2a5	1.95	0.003
			Q9ET30	Transmembrane 9 superfamily member 3	Tm9sf3	1.94	0.06
			Q3TGU7	Proliferation‐associated 2G4	Pa2 g4	1.93	0.01
			Q9JMG1	Endothelial differentiation‐related factor 1	Edf1	1.91	0.04
			Q9CZR8	Elongation factor Ts	Tsfm	1.79	0.01
	Down‐regulated	72	Q05816	Fatty acid‐binding protein, epidermal	Fabp5	0.36	0.004
			P63030	MPC 1	Mpc1	0.44	0.006
			Q9D0B5	Thiosulfate sulfurtransferase/rhodanese‐like domain‐containing protein 3	Tstd3	0.46	0.03
			Q8VCF0	Mitochondrial antiviral‐signalling protein	Mavs	0.51	0.07
			P62806	Histone H4	Hist1h4a	0.52	0.06
			A0A1W2P768	Histone H3.2	Hist2h3c1	0.55	0.10
			P62996	Transformer‐2 protein homolog beta	Tra2b	0.55	0.07
			A0A0N4SVP8	Predicted pseudogene 5580	Gm5580	0.56	0.01
			Q9D3D9	ATP synthase subunit delta	Atp5d	0.58	0.01
			Q62425	Cytochrome c oxidase subunit NDUFA4	Ndufa4	0.58	0.01
T 23 vs. T 30	Up‐regulated	34	Q9CXV1	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit	Sdhd	1.83	0.08
			Q9ESP1	Stromal cell‐derived factor 2‐like protein 1	Sdf2 l1	1.61	0.09
			Q9CR21	Acyl carrier protein	Ndufab1	1.61	0.09
			P00186	Cytochrome P450 1A2	Cyp1a2	1.42	0.08
			Q99L04	Dehydrogenase/reductase SDR family member 1	Dhrs1	1.41	0.01
			Q91X77	Cytochrome P450 2C50	Cyp2c50	1.40	0.09
			Q5HZI9	Solute carrier family 25 member 51	Slc25a51	1.39	0.06
			G3X9F4	Transmembrane protein 143	Tmem143	1.39	0.06
			P61027	Ras‐related protein Rab‐10	Rab10	1.38	0.06
			Q9DC16	ER‐Golgi intermediate compartment protein 1	Ergic1	1.38	0.08
	Down‐regulated	19	P62806	Histone H4	Hist1h4a	0.40	0.05
			P10922	Histone H1.0	H1f0	0.41	0.07
			A0A1W2P768	Histone H3.2	Hist2h3c1	0.42	0.09
			P63030	MPC 1	Mpc1	0.56	0.00
			Q64433	10 kDa heat shock protein	Hspe1	0.63	0.06
			P09671	Superoxide dismutase [Mn]	Sod2	0.65	0.07
			A0A0N4SVP8	Predicted pseudogene 5580	Gm5580	0.68	0.04
			F8VPU2	FERM, ARHGEF and pleckstrin domain‐containing protein 1	Farp1	0.69	0.07
			P61458	Pterin‐4‐alpha‐carbinolamine dehydratase	Pcbd1	0.70	0.05
			P10852	4F2 cell‐surface antigen heavy chain	Slc3a2	0.70	0.03