Table 3.
Susceptibilities of individual strains of Cryptococcus neoformans and Cryptococcus gattii to amphotericin B and tamoxifen, alone and in combination
| Isolate ID | MIC (µg/mL) | FIC index | |||
|---|---|---|---|---|---|
| Amphotericin B | Tamoxifen | ||||
| Alone | Combined | Alone | Combined | ||
| BK03 | 2 | 0.5 | 8 | 2 | 0.5 |
| BK20 | 0.5 | 0.25 | 4 | 2 | 1 |
| BK23 | 1 | 0.25 | 4 | 0.5 | 0.38 |
| BK33 | 1 | 0.25 | 16 | 4 | 0.5 |
| BK34 | 2 | 0.125 | 4 | 4 | 1.06 |
| BK42 | 0.5 | 0.25 | 4 | 0.5 | 0.63 |
| BK45 | 1 | 0.25 | 4 | 1 | 0.5 |
| BK48 | 0.5 | 0.125 | 4 | 1 | 0.5 |
| BK59 | 1 | 0.5 | 8 | 2 | 0.75 |
| BK62 | 0.5 | 0.125 | 4 | 1 | 0.5 |
| BK69 | 2 | 0.25 | 2 | 2 | 1.13 |
| BK73 | 2 | 0.5 | 16 | 0.25 | 0.27 |
| BK81 | 1 | 0.25 | 16 | 2 | 0.38 |
| BK84 | 1 | 0.25 | 16 | 2 | 0.38 |
| BK87 | 2 | 0.5 | 4 | 0.25 | 0.31 |
| BK91 | 2 | 0.5 | 16 | 0.5 | 0.28 |
| BK111 | 1 | 0.25 | 4 | 1 | 0.5 |
| BK115 | 0.5 | 0.25 | 2 | 1 | 1 |
| BK128 | 2 | 0.25 | 8 | 2 | 0.38 |
| BK139 | 1 | 0.25 | 4 | 1 | 0.5 |
| BK169 | 0.5 | 0.25 | 4 | 1 | 0.75 |
| BK175 | 1 | 0.25 | 4 | 0.25 | 0.31 |
| BK192 | 2 | 0.125 | 16 | 4 | 0.31 |
| BK224 | 0.25 | 0.125 | 4 | 2 | 1 |
| BK247 | 2 | 0.25 | 16 | 2 | 0.25 |
| BK287 | 1 | 0.25 | 8 | 2 | 0.5 |
| BK301 | 2 | 1 | 16 | 1 | 0.56 |
| BMD394 | 2 | 0.5 | 4 | 0.25 | 0.31 |
| BMD865 | 1 | 0.125 | 4 | 0.5 | 0.25 |
| BMD1392 | 2 | 0.125 | 4 | 4 | 1.06 |
| BMD800a | 1 | 0.125 | 8 | 4 | 0.63 |
| BMD856b | 2 | 0.5 | 2 | 0.25 | 0.38 |
| BMD1377b | 0.5 | 0.125 | 2 | 0.5 | 0.50 |
| BMD1516b | 0.5 | 0.125 | 4 | 0.25 | 0.31 |
| WM179 | 0.5 | 0.125 | 4 | 0.25 | 0.31 |
| WM178 | 0.25 | 0.125 | 4 | 0.25 | 0.56 |
| WM175 | 1 | 0.25 | 8 | 0.25 | 0.28 |
| WM779 | 0.5 | 0.125 | 4 | 0.25 | 0.31 |
| H99 | 1 | 0.25 | 4 | 2 | 0.8 |
a
C. deuterogattii.
b
C. gattii sensu stricto.