Figure 4.

miR‐22 inhibits the SCLC cells proliferation under different doses of γ‐irradiation. A, miR‐22 expression in cells were detected by qPCR. B, Cells were stimulated with the indicated concentrations of MTS for the indicated conditions, cell viability was determined by microplate reader detection. CB‐DC, Cells were cultured in 96‐well plates for the indicated conditions, cell number was determined by Giemsa staining. *,**,***Significant differences between the tested and the control strains, P < .05, P  < . 01, and P  < . 001, respectively. MTS, 3‐(4,5‐dimethylthiazol‐2‐yl)‐ 5‐(3‐carboxymethoxyphenyl)‐ 2‐(4‐sulfophenyl)‐2H‐tetrazolium; NC, negative contriol; qPCR, quantitative polymerase chain reaction; SCLC, small‐cell lung cancer