. 2019 Jul 22;98(11):6005–6018. doi: 10.3382/ps/pez407

Table 6.

Effect of interaction between age and intestinal segment on the relative mRNA expression of candidate genes of the transcellular pathway.

Gene		TRPV2	TRPM7	CALM1	CALB1	ATP2B2	ATP2B4
Age (wk)	Segment
12	Duodenum	42^b	61^a–c	71^a,b	16^b	46^b	19^e
		(16)	(8)	(6)	(11)	(38)	(6)
	Jejunum	118^a	38^c	65^b	1^b	64^b	104^a
		(15)	(8)	(6)	(11)	(38)	(6)
	Ileum	54^a,b	56^a–c	92^a,b	1^b	39^b	51^c–e
		(15)	(8)	(6)	(11)	(38)	(6)
15	Duodenum	92^a,b	101^a	81^a,b	15^b	94^b	29^c–e
		(16)	(9)	(6)	(11)	(41)	(6)
	Jejunum	53^a,b	68^a–c	78^a,b	3^b	35^b	58^c,d
		(15)	(8)	(6)	(11)	(38)	(6)
	Ileum	95^a,b	85^a,b	74^a,b	1^b	87^b	98^a,b
		(15)	(8)	(6)	(11)	(38)	(6)
17	Duodenum	65^a,b	89^a,b	82^a,b	43^b	123^b	25^d,e
		(16)	(8)	(6)	(11)	(38)	(6)
	Jejunum	52^a,b	60^a–c	83^a,b	13^b	53^b	46^c–f
		(15)	(8)	(6)	(11)	(38)	(6)
	Ileum	110^a	53^b,c	63^b	5^b	83^b	71^b,c
		(15)	(8)	(6)	(11)	(38)	(6)
23	Duodenum	74^a,b	88^a,b	96^a	143^a	381^a	31^c–e
		(14)	(8)	(5)	(10)	(35)	(5)
	Jejunum	70^a,b	86^a,b	90^a,b	109^a	53^b	54^c–e
		(14)	(8)	(5)	(11)	(35)	(5)
	Ileum	61^a,b	57^a–c	85^a,b	47^b	75^b	91^a,b
		(14)	(8)	(5)	(10)	(35)	(5)
Source of variation
	Age	0.860	0.002	0.011	<.0001	0.005	0.020
	Segment	0.599	0.000	0.548	<.0001	<.0001	<.0001
	Age x Segment	0.001	0.038	0.006	0.000	0.000	<.0001

Relative expression values, expressed as arbitrary units are presented as LSMeans with (SEM) with n = 5 to 7 per experimental group.

^a–f

Means with different superscripts within the same column are significantly different (P < 0.05).

TRPV2 = Transient receptor potential cation channel subfamily V member 2; TRPM7 = Transient receptor potential cation channel subfamily M member 7; CALM1 = Calmodulin; CALB1 = Calbindin 28K; ATP2B2 = ATPase plasma membrane Ca²⁺ transporting 2; and ATP2B4 = ATPase plasma membrane Ca²⁺ transporting 4.