Panel 1.

Overview of search terms used in this systematic review (formatted for MEDLINE)

(("Anxiety Disorders"[Mesh:NoExp] OR "Agoraphobia"[Mesh] OR "Anxiety, Separation"[Mesh] OR "Neurocirculatory Asthenia"[Mesh] OR "Neurotic Disorders"[Mesh] OR "Panic Disorder"[Mesh] OR "Phobic Disorders"[Mesh] OR anxiety disorder* [tiab] OR generalized anxiety disorder* [tiab] OR generalised anxiety disorder* [tiab] OR anxiety state* [tiab] OR agoraphobi* [tiab] OR panic* [tiab] OR phobi* [tiab] OR selective mutis* [tiab]))

AND

(“Retreatment” [Mesh] OR "Drug Resistance" [Mesh:NoExp] OR “Drug tolerance” [Mesh] OR treatment resistan* [tiab] OR refractor* [tiab] OR poor respon* [tiab] OR partial respon* [tiab] OR non‐respon* [tiab] OR nonrespon* [tiab] OR loss of respons* [tiab] OR medication resistan* [tiab] OR drug resistan* [tiab] OR tachyphyl* [tiab] OR resilien* [tiab] OR persistan* [tiab] OR immune [tiab] OR insusceptib* [tiab] OR irresponsive* [tiab] OR unreceptive* [tiab] OR resistive [tiab] OR unsuccessful treatment* [tiab] OR treatment failur* [tiab] OR failed treatment* [tiab] OR "Patient Dropouts"[Mesh] OR patient dropout* [tiab] OR treatment dropout* [tiab] OR "Patient Compliance"[Mesh] OR non‐complian* [tiab] OR noncomplian* [tiab] OR non‐adheren* [tiab] OR nonadheren* [tiab] OR remaining symptom* [tiab] OR pseudo‐resistan* [tiab] OR dropping out [tiab] OR augmentation [tiab] OR inadequate respon* [tiab] OR intractab* [tiab] OR partially respon* [tiab] OR resistant patient* [tiab] OR remain symptom* [tiab] OR remaining symptom* [tiab] OR non‐remitting [tiab] OR nonremitting [tiab] OR partial improvement* [tiab] OR incomplete respon* [tiab] OR residual symptom* [tiab] OR anxiolytic toleran* [tiab])