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. 2019 Jun 3;21(8):1925–1934. doi: 10.1111/dom.13753

Table 1.

Characteristics of the four profiles: Outcome = renal function preservation

Profile Learning dataset Validation dataset
N (%) Class effect (within the profile) Class benefit (within vs. without the profile) N (%) Class effect (within the profile) Class benefit (within vs. without the profile)
aOR P value Ratio of aORs P value aOR P value BHP value Ratio of aORs P value BH P value
A. Hyperlipidaemia No 724 (20) 2.2 0.0009 2.1 0.0025 296 (19) 2.7 0.0053 0.0639 2.8 0.0054 0.0646
eGFR ≥79 mL/min/1.73 m2
B. eGFR ≥79 mL/min/1.73 m2 556 (15) 2.7 0.0023 2.4 0.0074 238 (15) 3.0 0.0184 0.0752 2.9 0.0293 0.139
Duration of diabetes ≤1.2 years
C. eGFR ≥75 mL/min/1.73 m2 430 (12) 2.3 0.0032 2.2 0.0086 198 (13) 2.6 0.0212 0.0752 2.5 0.0348 0.139
Antithrombotic agents Yes
D. Haemoglobin ≤13.4 g/dL 384 (10) 2.7 0.0009 2.0 0.0254 176 (11) 3.3 0.0251 0.0752 2.6 0.073 0.2189
LDL cholesterol ≥95.1 mg/dL

Note: Bold font indicates statistical significance at risk levels of 5% for P values and 10% for BH P values.

Abbreviations: aOR, adjusted odds ratio; BH, Benjamini–Hochberg; eGFR, estimated glomerular filtration rate.