Figure 6.

Protein–protein interaction (PPI) network of DEGs and module analysis. (a) Based on the STRING online database, a DEG PPI network was constructed containing 94 DEGs (41 upregulated DEGs labeled in red and 53 downregulated DEGs labeled in blue). (b) Identification of two significant modules based on the degree of importance. Module 1 contains 8 nodes and 27 edges. (c) Module 2 contains 5 nodes and 7 edges. DEGs, differentially expressed genes; PPI, protein–protein interaction [Color figure can be viewed at wileyonlinelibrary.com]