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. 2019 Jun 18;234(12):23785–23797. doi: 10.1002/jcp.28947

Table 1.

Gene Ontology term enrichment analysis of DEGs in multiple myeloma

Term Description Count p value
Upregulated
GO:0022626 Cytosolic ribosome 6 4.39 × 10−6
GO:0006414 Translational elongation 6 1.27 × 10−5
GO:0033279 Ribosomal subunit 6 4.08 × 10−5
GO:0003735 Structural constituent of ribosome 6 5.19 × 10−5
GO:0044445 Cytosolic part 6 9.25 × 10−5
GO:0022625 Cytosolic large ribosomal subunit 4 2.06 × 10−4
GO:0006412 Translation 7 4.48 × 10−4
GO:0005840 Ribosome 6 4.64 × 10−4
GO:0015934 Large ribosomal subunit 4 1.10 × 10−3
GO:0005198 Structural molecule activity 7 4.04 × 10−3
Downregulated
GO:0048584 Positive regulation of response to stimulus 9 1.29 × 10−5
GO:0002684 Positive regulation of immune system process 9 1.37 × 10−5
GO:0006955 Immune response 14 1.39 × 10−5
GO:0002253 Activation of immune response 6 7.44 × 10−5
GO:0009611 Response to wounding 11 1.54 × 10−4
GO:0044421 Extracellular region part 14 2.02 × 10−4
GO:0002449 Lymphocyte mediated immunity 5 3.11 × 10−4
GO:0002252 Immune effector process 6 3.92 × 10−4
GO:0006952 Defense response 11 5.07 × 10−4
GO:0050778 Positive regulation of immune response 6 5.63 × 10−4

Abbreviations: DEGs, differentially expressed genes; GO, Gene Ontology.