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a) Cross‐linking of squaramate‐modified DNA (DNA_CESQ) with histone recombinant proteins. b) SDS‐PAGE analysis of cross‐linking experiments with natural or modified DNA and various recombinant proteins (2 equiv of protein to DNA): 17.5 % SDS‐PAGE gel. Conditions: phosphate buffer (4.5 mm, pH 7.4), 37 °C, 36 h.
