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. 2019 Jun 25;63(17):1900403. doi: 10.1002/mnfr.201900403

Figure 5.

Figure 5

Markers of glucose homeostasis and survey of body weight in ob/ob mice following a two‐week treatment with plant extract from Porphyra umbilicalis (Pum) or Melissa officinalis L. (Mel) or vehicle (veh). Kinetic analysis of A: fed blood glucose and B: body weight during the two weeks of treatment. C: oral glucose‐tolerance test (OGTT) with AUC (area under the curve) as inset. D: intraperitoneal insulin‐tolerance test (IPITT). Gene expression analysis of white adipose tissue (E) and liver (F) and related PCA as subpanel. G: Serum IL‐6 levels. Data are presented as mean ± SEM. n = 5; *p < 0.05, Kruskal–Wallis test (E, F) plus two‐stage step‐up method of Benjamini, Krieger and Yekutieli correction for multiple comparisons by controlling the false discovery rate (FDR < 0.05) vs control group ob/ob + veh or 1‐PERMANOVA (F, lower panel) with Bonferroni's corrections.