Table 1.
Characteristics of brains provided for study. MS cases and HCs
| Subject | Sex | Age | Hemisphere | Disease progression | Disease duration (years) | Time disease was progressive (years)a | Time in a wheelchair (years)a | PMI (h) | Scan interval (days) | Cause of death |
|---|---|---|---|---|---|---|---|---|---|---|
| MS 254 | F | 69 | R | Secondary | 37 | 12 | 7 | 66 | 1,198 | MS |
| MS 281 | F | 74 | L | Primary | 33 | 17 | 40 | 929 | Sepsis | |
| MS 314 | F | 78 | R | Secondary | 45 | 24 | 17 | 60 | 435 | Colonic carcinoma |
| MS 316 | F | 79 | R | Secondary | 55 | 40 | 36 | 26 | 1,052 | Pneumonia |
| MS 322 | M | 72 | L | Secondary | 28 | 4 | 59 | 1,201 | Pneumonia | |
| MS 332 | F | 50 | R | Secondary | 22 | 10 | 2 | 69 | 1,134 | Breast cancer mets |
| MS 334 | M | 66 | R | Secondary | 15 | 1 | 37 | 1,126 | Prostate cancer | |
| MS 396 | F | 86 | R | Primary | 54 | 54 | 578 | Lymphoma | ||
| MS 400 | F | 60 | L | Secondary | 11 | 7 | 21 | 539 | MS | |
| HC 1 | M | 72 | R | – | – | – | – | 24 | 693 | |
| HC 2 | F | 88 | R | – | – | – | – | 24 | 655 | |
| HC 3 | M | 68 | R | – | – | – | – | 48 | 1,236 | |
| HC 4 | F | 82 | L | – | – | – | – | 48 | 1,197 | |
| HC 5 | F | 68 | L | – | – | – | – | 48 | 1,216 | Pancreas carcinoma |
| HC 6 | F | 48 | R | – | – | – | – | 48 | 1,151 | Pneumonia |
Abbreviations: HC, healthy control; MS, multiple sclerosis; PMI, postmortem interval.
a
MS clinical details where data were not available for all cases.