Table 4.
Overall region differences for histology measurements in the MS brains determined by repeated measures ANOVAs are reported in the first row (effect of region). Post hoc t‐statistics are reported in the subsequent rows for specific region comparisons
| Region | Minicolumn width (μm) | Minicolumn spacing (μm) | Minicolumn core width (μm) | Minicolumn microsegment number/mm2 | Cell density | Axon bundle spacing (μm) | Axon bundle width (μm) |
|---|---|---|---|---|---|---|---|
| Effect of region |
F(2,14) = 22.523 p < .001* |
F(2,14) = 0.257 N.S. |
F(2,14) = 0.440 N.S. |
F(2,14) = 0.479 N.S. |
F(2,14) = 2.493 N.S. |
F(2,16) = 45.076 p < .001** |
F(2,16) = 18.345 p < .001** |
| Area 9 vs. Area 41 |
T = 2.189 p = .065 |
– | – | – | – |
T = −1.125 p = .293 |
T = −3.586 p = .007** |
| V1 vs. Area 41 |
T = −4.299 p = .004** |
– | – | – | – |
T = −7.340 p < .001** |
T = −6.559 p < .001** |
| Area 9 vs. V1 |
T = 9.013 p < .001** |
– | – | – | – |
T = 18.149 p < .001** |
T = 2.228 p = .056 |
Abbreviations: ANOVA, analysis of variance; MS, multiple sclerosis.