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Location of single nucleotide polymorphisms (SNPs) in the human TCF7L2 gene. Representative intron–exon structure of the TCF7L2 gene. Long introns are represented by a double slash. Blue boxes indicate the alternatively spliced exons, blue arrows represent alternative transcription start sites. Important protein domains are marked by red boxes: β‐catenin binding domain, and DNA binding domain ‐ HMG‐box. Black arrows indicate the location of SNPs or mutations.
