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Polyamine metabolism in humans. Schematic shows polyamines (putrescine, spermidine, and spermine), and their acetylated metabolites and converting enzymes. Ac‐CoA = acetyl‐coenzyme A; APAO = N1‐acetylpolyamine oxidase; ATP = adenosine triphosphate; CoA = coenzyme A; MTA = 5′‐deoxy‐5′‐methylthioadenosine; SAMHC = S‐adenosylmethyl homocysteamine; SAT1/2 = spermidine/spermine acetyltransferase 1/2.
