Table 5.
Patients’ Characteristics of PD with or without Diffusion Tensor Imaging
| Characteristic | PD | PD with Diffusion Tensor Imaging | p a |
|---|---|---|---|
| Age, mean yr (SD) | 67.6 (9.56) | 69.5 (10.0) | 0.406 |
| H&Y, mean (SD) | 2.05(0.907) | 2.15 (0.745) | 0.649 |
| UPDRS‐III, mean (SD) | 13.5 (9.89) | 11.4 (7.60) | 0.357 |
| L‐dopa, mean mg (SD) | 399 (239) | 413 (210) | 0.807 |
| MMSE, mean (SD) | 27.8 (3.10) | 26.7 (3.37) | 0.164 |
| L‐dopa equivalent dose, mean (SD) | 606 (357) | 607 (279) | 0.990 |
| DiAcSpd, mean (SD) | 0.704 (0.365) | 0.751 (0.430) | 0.590 |
| N1‐AcSpd, mean (SD) | 18.9 (10.8) | 21.9 (11.8) | 0.245 |
| N8‐AcSpd, mean (SD) | 11.2 (3.42) | 11.8 (3.03) | 0.451 |
| DiAcSpm, mean (SD) | 0.916 (0.689) | 0.861 (0.431) | 0.728 |
| Spd, mean (SD) | 23.6 (11.9) | 24.7 (14.9) | 0.726 |
| N1‐AcSpm, mean (SD) | 0.496 (0.280) | 0.549 (0.346) | 0.434 |
| Spm, mean (SD) | 4.24 (2.00) | 4.47 (2.09) | 0.621 |
| Spm/Spd ratio, mean (SD) | 0.208 (0.118) | 0.220 (0.115) | 0.666 |
a
Probability values were obtained by Wilcoxon test between PD and PD with diffusion tensor imaging.
DiAcSpd = N1,N8‐diacetylspermidine; DiAcSpm = N1,N12‐diacetylspermine; H&Y = Hoehn and Yahr stage; MMSE = Mini‐Mental State Examination; N1‐AcSpd = N1‐acetylspermidine; N1‐AcSpm = N1‐acetylspermine; N8‐AcSpd = N8‐acetylspermidine; PD = Parkinson disease; SD = standard deviation; Spd = spermidine; Spm = spermine; UPDRS‐III = Unified Parkinson's Disease Rating Scale motor section.