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. 2000 Apr 15;20(8):2978–2987. doi: 10.1523/JNEUROSCI.20-08-02978.2000

Fig. 5.

Fig. 5.

Temporal patterns of BDNF content in the SCN of wild-type and heterozygous BDNF knock-out mice. Symbolsrepresent the mean values (±SEM) of BDNF protein expression in the SCN of wild-type mice (WT:bdnf+/+) and BDNF knock-out mice (HET: bdnf+/−) killed at 4 hr intervals (n = 4) in DD. Circadian times during which BDNF levels in bdnf+/+mice were significantly greater (*p < 0.05) in comparison with those observed at CT 0, 4, and 8 are indicated. Comparisons of bdnf+/+ andbdnf+/− mice revealed significant differences (⋆p < 0.05) in SCN content of BDNF at all times.