Table 1.

Summary of experiments

Experiment	Control number of rats	Experimental number of rats	Age when infusion began1-a	Duration of infusion (days)	Age when infusion stopped1-a	Age when results were obtained1-a
2-Deoxyglucose studies	5	5	12	14	26	26
Cresyl violet studies	5	5	12	28	40	40
In vivo EEG studies
Recovery of neuronal activity after activity blockade	6	15	12–17	28	40–45	40–54
Age dependence of effects of ac	6	11	10–12	28	38–40	38–52
tivity blockade1-b	6	10	13–17	28	41–45	41–57
	2	6	45–50	28	73–78	73–90
Follow-up at 6–8 months of age	2	7	10–12	28	38–40	6–8 months
Interictal spikes in dorsal vs ventral hippocampus	5	5	10–12	28	38–40	26–40
Long-term video monitorings	2	7	10–12	28	38–40	6–12 months
In vitro slice studies
Recordings of remote focus in vitro	3	5	10–12	14–21	24–33	24–33
Recordings of epileptiform bursts 2 weeks after TTX withdrawal	2	3	10–12	28	38–40	52–54
Blockade of minibursts by:
KYN		3	10–12	14–21	24–33	24–33
CNQX		3	10–12	14–21	24–33	24–33
Whole-cell recordings	3	7	10–12	14–24	24–33	24–33

^F1-a Age in postnatal days.

^F1-b Some animals in this study were also included in recovery of neuronal activity data.