NMDAR immunoparticle density at synapses on spines. A, C, E, There is a weak positive correlation between the size and the NMDA receptor immunoparticle content of synapses (p < 0.01, Spearman rank correlation). A, For rat 1, slope of regression line = 155.4 gold/μm2. C, For rat 2, slope of regression line = 78.1 gold/μm2. E, For rat 3, slope of regression line = 153.0 gold/μm2.B, D, F, The gold particle density (number of particles per square micrometer) for NMDARs is weakly and negatively correlated with synapse size (Spearman rank correlation).