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Effects of brief binocular activity blockade on BDNF mRNA levels in the superior colliculus. Shown are dark-field photomicrographs of in situ hybridization for BDNF mRNA on coronal sections through the superior colliculus after binocular injections of citrate vehicle (a) or tetrodotoxin (b) at P43 and examination at P45. Reduction in cellular hybridization after TTX treatment is present only in superficial layers (outlined). Medial is to theleft and dorsal is up. Scale bar, 500 μm.
