Electron micrographs showing synaptic associations (arrows) between pro-TRH-containing neurons in the PVN and α-MSH-containing axon terminals. The pro-TRH-IR dendrites and perikarya are labeled with highly electron-dense silver granules, whereas the α-MSH-IR terminals are recognized by the presence of the electron-dense DAB. A, Medium-power magnification view of an axodendritic synapse, shown in greater detail in theinset. B, High-power magnification of an axosomatic synapse. Scale bars: A, 1 μm; B, inset, 0.4 μm.