Fig. 10.

Slow direct and indirect AMPAR-mediated EPSCs are present at 34°C. A, Direct AMPAR EPSCs evoked by five pulses at 100 Hz at low (top) or high (middle) stimulus intensity and a comparison of the responses scaled to the last peak (bottom).B, Direct AMPAR EPSCs evoked by five pulses at 100 Hz (S1) (i) and indirect AMPAR EPSCs evoked by 20 pulses at 100 Hz (S2) (ii). Addition of 10 μm NBQX blocked the indirect response (iii). Recordings were made at −40 mV, and 50 μmd-AP-5 was present for all experiments. Scale bar in Bi applies to Bi andBii. Recordings in A and Bare from different cells, and traces are averages of 5–20 trials.