Table 1.

Effects of oral administration of creatine on survival in R6/2 mice

	Unsupplemented R6/2 mice	1% Creatine-supplemented R6/2 mice	2% Creatine-supplemented R6/2 mice	3% Creatine-supplemented R6/2 mice
Days	97.7  ± 0.7	106.6  ± 0.5*	114.6  ± 0.9*	101.9  ± 1.01-160

Oral administration of 1, 2, and 3% creatine in the diet dose-dependently improved survival in R6/2 transgenic mice. Oral administration of 2% creatine was significantly greater than 3% creatine (p < 0.0001).

^*p < 0.0001;

F1-160: p < 0.0002.