Skip to main content
. 2000 Mar 15;20(6):2255–2265. doi: 10.1523/JNEUROSCI.20-06-02255.2000

Table 4.

Effect of thyroid hormone on NSP and Oct-1 mRNA in the adult brain (Experiment IV)

Thyroid status Brain region NSP mRNA Oct-1 mRNA
Control Cortex 100.00  ±  2.44 (5) 100.00  ±  0.45 (5)
T3 99.12  ±  1.85 (6) 92.70  ±  1.58 (6)**
MMI + PTU 104.00  ±  2.58 (6) 99.45  ±  0.77 (6)
MMI + PTU + T3 101.01  ±  1.22 (6) 95.71  ±  1.40 (6)*
Control Dentate gyrus 100.00  ±  1.73 (5) 100.00  ±  1.66 (5)
T3 98.51  ±  0.71 (5) 96.01  ±  1.48 (6)*
MMI + PTU 105.09  ±  1.08 (5)* 101.09  ±  0.52 (6)
MMI + PTU + T3 100.01  ±  1.27 (6) 95.99  ±  0.81 (6)*
Control CA14-a 100.00  ±  1.09 (4) 100.00  ±  1.55 (4)
T3 105.27  ±  1.75 (6) 97.94  ±  1.57 (6)
MMI + PTU 108.80  ±  2.08 (6)* 101.97  ±  1.11 (6)
MMI + PTU + T3 104.17  ±  1.27 (6) 97.42  ±  1.13 (6)
Control CA24-a 100.00  ±  .67  (3) 100.00  ±  1.10 (5)
T3 101.36  ±  1.65 (6) 95.82  ±  0.98 (6)*
MMI + PTU 105.93  ±  1.54 (5) 99.37  ±  0.20 (4)
MMI + PTU + T3 100.20  ±  1.15 (6) 95.11  ±  10.4 (6)**
Control CA34-a 100.00  ±  0.85 (4) 100.00  ±  0.26 (5)
T3 100.64  ±  0.68 (4) 94.00  ±  1.86 (6)**
MMI + PTU 105.51  ±  1.81 (6) 98.90  ±  0.92 (6)
MMI + PTU + T3 101.30  ±  1.26 (6) 93.32  ±  0.81 (6)**
Control Cerebellum 100.00  ±  1.64 (4) 100.00  ±  0.40 (4)
T3 97.58  ±  0.61 (6) 100.14  ±  0.62 (6)
MMI + PTU 97.86  ±  0.31 (5) 101.60  ±  1.01 (6)
MMI + PTU + T3 95.2  ±  1.48 (6) 100.29  ±  0.17 (6)

Quantitive analysis of autoradiograms after in situhybridization for NSP and Oct-1 mRNA in the cortex, hippocampus, and cerebellum of thyroid hormone-manipulated adult rats. Values shown represent mean + SEM (n) of film density (converted to % controls ± CV) over the cortex, hippocampus, or cerebellum.

* Significantly different from control euthyroid rats receiving saline injections (p < 0.05).

** Significantly different from control euthyroid rats receiving saline injections (p < 0.01).

F4-a

 Subfields of Ammon's horn.