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CGS 21680 (100 nm) significantly enhanced stimulation-evoked GABA release from striatal/pallidal slices from D2R+/+ mice but not from D2R+/− or D2R−/− mice. See Figure 1 for experimental details. Mean values ± SEM are shown forn = 6 mice (D2R+/+, D2R−/−) or n = 8 mice (D2R+/−). Two-factor ANOVA with repeated measures (drug) followed by Newman–Keuls post hoc comparisons: *p < 0.05, D2R+/+ control versus CGS 21680.
