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Density of SYN-IR presynaptic terminals does not correlate with plaque load in mice from different FAD-mutant hAPP lines. Plaque load and density of SYN-IR presynaptic terminals in the hippocampus were determined in 31 transgenic mice from APPInd lines H6, H9, and H40 and APPSw, Indline J9 at 21–27 months of age. No correlation was found between the two variables.
