Table 1.

Data from male and female wild-type and ERαKO mice tested for masculine sexual behavior

Sex Genotype Treatment	Latency to mount (min)	Latency to thrust (min)	Number of mount bouts	Number of bouts with thrusts	Latency to intromit (min)	Latency to ejaculate (min)	Intro. to ejaculation interval (min)
Male WT Vehicle	25.5  ± 3.06  (10)	38.9  ± 6.38  (10)	13.1  ± 2.83  (10)	10.3  ± 2.01  (10)	57.7  ± 6.24  (10)	77.1  ± 2.82  (7)	26.14  ± 6.45  (7)
Male WT APO	27.0  ± 3.71  (10)	48.8  ± 3.73  (10)	11.0  ± 1.95  (10)	11.1  ± 2.24  (10)	71.9  ± 5.06  (10)	73.2  ± 3.4  (6)	9.67  ± 3.32  (6)
Male ERαKO APO	25.9  ± 3.91  (10)	41.2  ± 5.13  (10)	15.8  ± 3.05  (10)	10.9  ± 2.21  (10)	70.0  ± 3.97  (10)	77.0  ± 2.39  (5)	10.8  ± 4.45  (5)
Female WT Vehicle	55.0  ± 10.66  (6)	58.2  ± 8.72  (6)	5.0  ± 1.43  (6)	4.83  ± 1.25  (6)	NA	NA	NA
Female WT APO	56.3  ± 8.13  (7)	65.7  ± 9.23  (7)	5.57  ± 1.39  (7)	6.0  ± 1.53  (7)	NA	NA	NA
Female ERαKO APO	60.4  ± 7.04  (7)	71.3  ± 7.82  (7)	10.0*  ± 0.65  (7)	4.14  ± 0.86  (7)	NA	NA	NA

Data from ERαKO animals that received vehicle treatment are not included because none of these mice displayed masculine sexual behavior. Data given are means ± SEM. Numbers of mice per group is given in parentheses.

*Significant genotype difference within same sex. NA, Not applicable; WT, wild-type mice; ERαKO, estrogen receptor α knock-out littermates.