Fig. 11.

Activity of a single Acb cell during the multiple schedule for food and cocaine reinforcement. Left, PEHs show that the Acb cell exhibited type RFe activity relative to the food-reinforced response (top). The same Acb cell exhibited NP activity relative to the cocaine-reinforced response (bottom). Mean INT for food = 20.81 ± 0.04 sec; mean INT for cocaine = 4.16 ± 0.14 min.Right, Raster display shows the activity of the same neuron shown in the PEHs across all trials (number indicated atfar right) of the multiple schedule. The transition to NP activity during the self-administration portion of the multiple schedule was immediate, and maintained throughout the remainder of the session.