Table 1.

Mean response rates (responses per second) during microdialysis studies

Animal	M103	M32	M49	M47
Precue	0.012  ± 0.005 (5)	0.11  ± 0.03 (10)	0.014  ± 0.004 (19)	0.009  ± 0.003 (19)
Cue (cocaine)	1.47  ± 0.18 (5)	1.29  ± 0.31 (6)	1.03  ± 0.16 (14)	1.38  ± 0.15 (14)
Cue (saline)	1.18  ± 0.17 (5)	3.20  ± 0.80 (4)	1.62  ± 0.28 (4)	1.60  ± 0.30 (4)
Post-saline	0.007  ± 0.007 (5)	—	0.01  ± 0.008 (4)	0.001  ± 0.0003 (5)

Cue (cocaine or saline) rate refers to that during the time the visual stimulus was on, with either cocaine or saline delivered after achieving contingency. Saline infusions were not part of an extinction procedure, but were occasional “surprise” substitutions. Post-saline rates (presented for animals 103, 49, and 47 for comparison to Fig. 9) were calculated over the period from cue offset to the first lever press more than 10 min after infusion. For each animal, mean rates before cue presentation differed from the mean response rates during the time the cue was on, as did rates after saline and after cocaine (data not shown, but essentially the same as after saline,p < 0.05). Numbers in parentheses indicate number of observations.