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Dose–response curves of the effect of intrathecal SHU9119 (A), MTII (B), andd-Tyr-MTII (B) on von Frey withdrawal thresholds in neuropathic rats. Values represent threshold at 30 min after injection as a percentage of baseline threshold. Data are presented as mean ± SEM of 10 rats each, except 1.5 μg of SHU9119 (n = 4).
