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. 2000 Nov 1;20(21):8131–8137. doi: 10.1523/JNEUROSCI.20-21-08131.2000

Fig. 8.

Fig. 8.

Summary of the effects of intrathecal. administration of the MC3-R-selective ligand Nle-γ-MSH (5 μg), the MC4-R-selective ligands MTII (500 ng) and d-Tyr-MTII (3 μg), and the MC-R antagonist SHU9119 (1.5 μg) on the responses of CCI and control rats to different stimuli (indicated onx-axis). Values represent thresholds at 30 min (MTII,d-Tyr-MTII, and Nle-γ-MSH) or 15 min (SHU9119) after injection as a percentage of baseline threshold. Data are presented as mean ± SEM of 11 (control) or 10 (CCI) rats each, except 1.5 μg of SHU9119 (n = 4 CCI rats).