Table 1.

	B	C	D	E	F	G	H	I	J	K	L	M
2	0.010	Mitochondrial volume (fraction)
3	50	External probe conc. (nm)
4	0.020	Plasma membrane rate constant k (sec−1)
5	50	Quench limit (μm)
6	30	Interval (sec)

	Time (sec)	Δψp (mV)	Δψm(mV)	Equil [cyto] (nm)	Equil [matrix] (nm)	Virtual Cytoplasmic volume	Total probe	Actual [cyto] (nm)	Actual [matrix] (nm)	Invoking Quench limit	Matrix signal	Total signal
11	0	−60	−150	473	129899	3.7	1772	473	129899	50000	500	973
12	30	−20	−150	106	29053	3.7	1551	414	113755	50000	500	914
13	60	−20	−150	106	29053	3.7	1367	365	100196	50000	500	865
14	90	−20	−150	106	29053	3.7	1211	323	88807	50000	500	823
15	120	−20	0	106	106	1.0	1081	1070	1070	1070	11	1081
16	150	−20	0	106	106	1.0	502	497	497	497	5	502
17	180	−20	0	106	106	1.0	267	265	265	265	3	267