Fig. 1.

Representative molds from sweating assays. Sweating was induced in anesthetized P21 mice by treatment with the muscarinic agonist pilocarpine, and molds were made of the hind footpads with a dental impression material. Each active gland appears as a dark dot (arrows). Many glands are active in the interdigital pads of both pigmented and albino TH wild-type mice. Approximately one-third of the normal number of glands can be detected in the pads of pigmented TH null mice. Only a rare gland is active in the pads of the albino TH null mice.