Fig. 1.
A, Anxiety-like behavior in HR and LR rats in the light/dark boxes. Compared with LR rats, the HR rats exhibit a shorter latency to emerge from the dark to the light compartment. B, These HR rats spend more time in the light compartment. C, Minute-by-minute anxiety-like behavior in HR and LR rats in the light/dark boxes D, Anxiety-like behavior in HR and LR rats in the elevated plus maze. Compared with LR rats, HR rats spent more time in the open arms and the middle portion of the maze. HR rats spent less time than LR rats in the closed arms. Data are expressed as mean ± SEM. *p < 0.05.