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Suppression of cerebellar iNOS expression by PPARγ agonists. A mixture of LPS (10 μg) plus IFN-γ (20 U) dissolved in PBS was microinjected into rat cerebellum alone (none) or with ibuprofen (Ibu), troglitazone (Trog), or 15d-PGJ2(PGJ2). Injection of PBS only served as control (PBS). Levels of iNOS (A) and bNOS (B) were determined 24 hr after injections by Western blot analysis. The blots shown are representative of two independent experiments.
